P. Graham Dunn Porch Outstanding Rules Enjoy Classic Pine 14 60 Wood White x $44 P. Graham Dunn Porch Rules Enjoy Classic White 60 x 14 Pine Wood Home Kitchen Home DÃ©cor Products P. Graham Dunn Porch Outstanding Rules Enjoy Classic Pine 14 60 Wood White x Pine,Classic,Wood,14,Graham,$44,Dunn,leonkulik.com,Porch,x,P.,Rules,Home Kitchen , Home DÃ©cor Products,White,Enjoy,60,/Albococcus1517331.html $44 P. Graham Dunn Porch Rules Enjoy Classic White 60 x 14 Pine Wood Home Kitchen Home DÃ©cor Products Pine,Classic,Wood,14,Graham,$44,Dunn,leonkulik.com,Porch,x,P.,Rules,Home Kitchen , Home DÃ©cor Products,White,Enjoy,60,/Albococcus1517331.html
P. Graham Dunn is a family owned and operated business that opened its doors in 1976. Handcrafted character combined with modern computerized carving and laser operations, all based in the heart of Amish country in Dalton, Ohio, makes this company truly special. Today P. Graham Dunn serves over 4,000 accounts, most in the U.S., and the remainder in Canada and around the world. Farmhouse chic design gives hope, inspiration, and encouragement; Features sentiment that reads "Porch Rules, Enjoy each season, Visit with friends, Take a nap, Relax, Feel the breeze, Read a book, Put your feet up, Gather with family, Enjoy the day, Watch the sunset". Crafted from natural kiln-dried pine wood slats that provide authenticity to the hand-assembled signage; Includes a sawtooth hanger for optional wall application. Measures approximately 60 x 14 x 0.68 inches; Perfect for the porch to display outside next to an entryway door to greet friends and family. P. Graham Dunn products are designed and made in the USA; Handmade by artisans resulting in beautiful home decor. Individually wrapped in protective packaging; Ready for thoughtful gifting and inspiration
Molecular pathway of estrogen receptor (ER) action. Typically, estrogen binds to the ligand-binding domain of receptors in the nucleus, which causes a conformational change. Estrogen-responsive elements (ERE) mediate genomic effects. RE, response element; TF, transcription factor; GF, growth factor; GF-R, growth factor receptor; CoA, co-activator; CoR, co-repressor; MAPK, mictogen-activated protein kinase; PI3K, phophoinositide 3-kinase; Src, proto-oncogene tyrosine-protein kinase; AP-1, activating protein-1; Sp-1, stimulating protein-1. Adapted from Nie et al.16
Measurement parameters utilized to determine the esophageal motor function. (A) Esophagogastric junction (EGJ). (B) Esophageal body. EGJ-CI, esophagogastric junction-contractile integral; IRP, integrated relaxation pressure; LES, lower esophageal sphincter.
High-resolution manometry test swallows and maneuvers. (A) Supine 5 mL liquid; (B) upright 5 mL liquid; (C) viscous (apple sauce); (D) solid (graham cracker); (E) multiple rapid swallow; and (F) rapid drink challenge. Integrated relaxation pressure (IRP) and distal contractile integral (DCI) were 11 mmHg and 1760 mmHg·cm·sec (A), 8 mmHg and 1950 mmHg·cm·sec (B), 7 mmHg and 1600 mmHg·cm·sec (C), 10 mmHg and 1400 mmHg·cm·sec (D), 4 mmHg and 4600 mmHg·cm·sec (E), and 3 mmHg and 0 mmHg·cm·sec (F), respectively. Figure used with permission from the Esophageal Center at Northwestern.
Our diagnostic algorithm of defecation disorders using a colonic transit study. DD, defecation disorders; DRE, digital rectal examination; NTC, normal transit constipation; STC, slow transit constipation; RS, rectosigmoid colon.
Statistical maps showing voxel-mirrored homotopic connectivity (VMHC) differences between irritable bowel syndrome (IBS) and healthy controls (HCs;